Contact Lens-Induced Corneal Peripheral Swelling Differences With Extended Wear

Cornea October 2008, 27:9

Corneal thickness was measured in 5 corneal locations (central, superior, inferior, nasal, and temporal) with Orbscan II pachymetry 1 week before the wearing of CLs and after 1 week of EW. High-Dk (lotrafilcon A) and low-Dk (etafilcon A) soft CLs were randomly fitted for EW in the right and left eyes of 20 subjects with normal ocular health. Orbscan was also performed before CL removal after 3 and 7 days of EW.
.... Lotrafilcon A induced a lower percentage of corneal swelling in all 5 corneal locations than etafilcon A (P <> 0.05, repeated-measures analysis of variance).
Conclusions: Central and peripheral corneal thicknesses increase more with etafilcon A than with lotrafilcon A during EW, as measured by Orbscan pachymetry